Acute coronary syndrome associated with essential thrombocythemia

Calreticulin Mutated Essential Thrombocythemia Presenting as Acute Coronary Syndrome

Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by a clonal expansion of megakaryocytes. ET can result in both arterial and venous thrombosis. Involvement of the coronary arteries has been reported. Patients who harbor a CALR mutation are half as likely to suffer a thrombotic event as compared to patients with a JAK2 mutation. We report a case of CALR-mutated ET wh...

Systemic mastocytosis associated with essential thrombocythemia.

Mastocytosis comprises a spectrum of disorders characterized by abnormal growth of mast cells (MS). Four entities are recognizable according to WHO classification. Association of systemic mastocytosis (SM) with a chronic myeloproliferative neoplasia (SM-AHNMD) is the second frequently category. Published descriptions of the clinicopathologic features of SM-AHNMD are largely limited to individua...

Essential thrombocythemia associated with angina pectoris with unusual coronary artery findings.

A case of ET associated with angina pectoris is presented. Angiography showed a 3.0-cm long mosaic-like thrombus shadow consisting of small filling defects in the proximal left anterior descending artery. The lesion could not be reduced with warfarin, ticlopidine, trapidil, urokinase or melphalan. Coronary artery bypass grafting was performed successfully.

Acute coronary syndrome associated with phencyclidine use

Introduction: Many studies have documented the deleterious effects of psychoactive substances like cocaine and amphetamines on the coronary vasculature. However, the impact of phencyclidine (PCP) on the arteries of the heart has largely gone unrecorded. Case Report: We report a case of a 41-year-old female presented to our hospital with chest heaviness, shortness of breath, and nausea, which st...

Essential thrombocythemia and acute myocardial infarction.